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Donna Shields Selected Research

JP4-039

1/2020Fanconi Anemia Mouse Genotype-specific Mitigation of Total Body Irradiation by GS-Nitroxide JP4-039.
3/2017Induction of TGF-β by Irradiation or Chemotherapy in Fanconi Anemia (FA) Mouse Bone Marrow Is Modulated by Small Molecule Radiation Mitigators JP4-039 and MMS350.
2/2016Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(-/-) (C57BL/6) Mice.
7/2014Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.

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Donna Shields Research Topics

Disease

6Fanconi Anemia (Fanconi's Anemia)
01/2020 - 11/2011
5Pulmonary Fibrosis (Fibrosing Alveolitis)
11/2021 - 01/2004
3Fibrosis (Cirrhosis)
11/2021 - 01/2004
3Neoplasms (Cancer)
03/2019 - 05/2012
2Mucositis
01/2018 - 07/2014
1Ovarian Neoplasms (Ovarian Cancer)
01/2022
1Sepsis (Septicemia)
01/2020
1Paralysis (Palsy)
05/2019
1Epilepsy (Aura)
05/2012
1Trigeminal Neuralgia (Tic Douloureux)
05/2012
1Squamous Cell Carcinoma of Head and Neck
11/2011

Drug/Important Bio-Agent (IBA)

5nitroxylIBA
01/2020 - 11/2011
4JP4-039IBA
01/2020 - 07/2014
4MMS350IBA
01/2019 - 11/2013
3Proteins (Proteins, Gene)FDA Link
03/2019 - 11/2013
3Drinking WaterIBA
01/2019 - 11/2013
2CytokinesIBA
01/2022 - 03/2017
2RNA (Ribonucleic Acid)IBA
11/2021 - 03/2019
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2021 - 11/2021
1Interleukin-22 (IL-22)IBA
01/2022
1Biomarkers (Surrogate Marker)IBA
11/2021
1Silicon Dioxide (Silica)FDA LinkGeneric
11/2021
1Leucine (L-Leucine)FDA Link
01/2020
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2020
1Green Fluorescent ProteinsIBA
05/2019
1CesiumIBA
05/2019
1Transforming Growth Factor beta (TGF-beta)IBA
03/2017
1AntioxidantsIBA
02/2016
1TEMPOIBA
02/2016
1von Willebrand FactorIBA
07/2014
1EmulsionsIBA
07/2014
1sulfoxideIBA
11/2013
1LuciferasesIBA
11/2013
1LithiumIBA
05/2012
1Carbamazepine (Tegretol)FDA LinkGeneric
05/2012
1Valproic Acid (Depakote)FDA LinkGeneric
05/2012
1Sodium Channel BlockersIBA
05/2012
1DNA (Deoxyribonucleic Acid)IBA
11/2011
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
01/2004
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2004
1Biological ProductsIBA
01/2004

Therapy/Procedure

2Oral Administration
01/2022 - 01/2019
2Radiotherapy
07/2014 - 11/2011
1Transplantation
05/2019
1Drug Therapy (Chemotherapy)
03/2017
1Hematopoietic Stem Cell Transplantation
11/2011